News & Events: Post-traumatic pulmonary embolism

UCSF surgeon-scientist Lucy Zumwinkle Kornblith, MD is a co-investigator on a newly awarded $2M Department of Defense Congressionally Directed Medical Research Program in collaboration with the UCSF Department of Laboratory Medicine, and OHSU Division of Trauma, Critical Care, and Acute Care Surgery, for the study of "Freeze Dried Platelet Extracellular Vesicles as a Hemostatic Adjunct to Resuscitation for Prolonged Field Care." The DOD/CDMRP funded study is a multicenter, multi-investigator grant with primary investigators Dr. Shibani Pati (Department of Lab Medicine, UCSF) and Dr. [...]

Lucy Kornblith, M.D., Assistant Professor of Surgery in the UCSF Department of Surgery at ZSFG, is the 2019 recipient of The Irene Perstein Award for 2019, awarded by the UCSF School of Medicine to an outstanding, newly recruited, junior woman scientist. This unique award honors the legacy of Ms. Irene Perstein, who donated funds to support junior women faculty at UCSF. The highly competitive award is based on criteria including the novelty and innovation of the science, and the potential impact on human health. This award supports Dr. Kornblith's expansion of her investigations to include [...]

UCSF trauma surgeon Lucy Kornblith, M.D. has been awarded a 5-Year $1M National Institutes of Health (NIH) K23, Mentored Patient-Oriented Research Award to study to post-injury platelet biology. The award, through the National Institute of General Medical Studies, will support Dr. Kornblith's research through 2023.  The grant titled "Post-Injury Platelet Biology: Mechanisms and Outcomes", supports translational patient-oriented research. Specifically, Dr. Kornblith will investigate causal pathways, mechanisms, and associated outcomes of altered post-injury platelet biology in a prospective [...]

The National Trauma Institute recently issued an update on the progress of CLOTT Study, a 2nd phase that will more closely investigate the role of platelet biology in post-traumatic pulmonary embolism. To that end, UCSF surgeon-scientist Lucy Kornblith, M.D. has been recruited by principal investigator M. Margaret "Peggy" Knudson, M.D., FACS.  Following a productive investigation of the incidence of pulmonary thrombi after injury and the role of clot breakdown in the development of post-traumatic pulmonary embolism, the CLOTT study group (Consortium of Leaders in the Study of Traumatic [...]

The CLOTT (Coalition of Leaders in Thromboembolism) study group, led by trauma surgeon M. Margaret "Peggy" Knudson, M.D., FACS, has begun enrolling patients in a landmark clinical trial looking at the treatment and prevention of post-traumatic pulmonary embolism. The study, which includes  investigators at 17 Level 1 trauma centers, is funded by a $4.25M grant from the Defense Medical Research and Development Program (DMRDP).  Dr. Knudson, the study's principal investigator, is a professor of surgery and member of the UCSF Department of Surgery at Zuckerberg San Francisco General Hospital [...]