University of California San Francisco

Lucas Wachsmuth
Lucas Wachsmuth, MD, PhD

Resident (PGY-1)
General Surgery

    Education

    Institution Degree Dept or School End Date
    Duke University MD, PhD Tumor Immunology 05/2025
    University of Georgia BS Biochemistry, Biology 05/2014

    Publications

    MOST RECENT PUBLICATIONS FROM A TOTAL OF 16
    1. Antigen presentation by tumor-associated macrophages drives T cells from a progenitor exhaustion state to terminal exhaustion.
      Waibl Polania J, Hoyt-Miggelbrink A, Tomaszewski WH, Wachsmuth LP, Lorrey SJ, Wilkinson DS, Lerner E, Woroniecka K, Finlay JB, Ayasoufi K, Fecci PE| | PubMed
    2. Combination checkpoint blockade and laser interstitial thermal therapy in radiographically progressive non-small cell lung cancer brain metastases.
      Haskell-Mendoza AP, Srinivasan ES, Gonzalez AT, Reason EH, Jackson JD, Flusche AM, Wachsmuth LP, Lerner E, Underwood D, Buckley ED, Zaidi SE, Herndon JE, Fecci PE| | PubMed
    3. The LITT Fit in neuro-oncology: indications, imaging, and adjunctive therapies.
      Haskell-Mendoza AP, Gonzalez AT, Reason EH, Flusche AM, Chongsathidkiet P, Wachsmuth LP, Goodwin CR, Fecci PE| | PubMed
    4. Gold Nanostars Obviate Limitations to Laser Interstitial Thermal Therapy (LITT) for the Treatment of Intracranial Tumors.
      Srinivasan ES, Liu Y, Odion RA, Chongsathidkiet P, Wachsmuth LP, Haskell-Mendoza AP, Edwards RM, Canning AJ, Willoughby G, Hinton J, Norton SJ, Lascola CD, Maccarini PF, Mariani CL, Vo-Dinh T, Fecci PE| | PubMed
    5. CD8+ T cells maintain killing of MHC-I-negative tumor cells through the NKG2D-NKG2DL axis.
      Lerner EC, Woroniecka KI, D'Anniballe VM, Wilkinson DS, Mohan AA, Lorrey SJ, Waibl-Polania J, Wachsmuth LP, Miggelbrink AM, Jackson JD, Cui X, Raj JA, Tomaszewski WH, Cook SL, Sampson JH, Patel AP, Khasraw M, Gunn MD, Fecci PE| | PubMed
    6. Foxn1 overexpression promotes thymic epithelial progenitor cell proliferation and mTEC maintenance, but does not prevent thymic involution.
      Li J, Wachsmuth LP, Xiao S, Condie BG, Manley NR| | PubMed
    7. Posttransplantation cyclophosphamide expands functional myeloid-derived suppressor cells and indirectly influences Tregs.
      Fletcher RE, Nunes NS, Patterson MT, Vinod N, Khan SM, Mendu SK, Li X, de Paula Pohl A, Wachsmuth LP, Choo-Wosoba H, Eckhaus MA, Venzon DJ, Kanakry CG| | PubMed
    8. Systemic immune derangements are shared across various CNS pathologies and reflect novel mechanisms of immune privilege.
      Lorrey SJ, Waibl Polania J, Wachsmuth LP, Hoyt-Miggelbrink A, Tritz ZP, Edwards R, Wolf DM, Johnson AJ, Fecci PE, Ayasoufi K| | PubMed
    9. Erratum to "E.C. Lerner, E.S. Srinivasan, G. Broadwater, et al. Factors Associated With New-Onset Seizures Following Stereotactic Radiosurgery for Newly Diagnosed Brain Metastases. Adv Radiat Oncol. 2022;7:101054."
      Lerner EC, Srinivasan ES, Broadwater G, Haskell-Mendoza AP, Vaios EJ, Edwards RM, Wachsmuth LP, Huie D, Floyd SR, Adamson JD, Fecci PE| | PubMed
    10. Efflux capacity and aldehyde dehydrogenase both contribute to CD8+ T-cell resistance to posttransplant cyclophosphamide.
      Patterson MT, Nunes NS, Wachsmuth LP, Panjabi A, Fletcher RE, Khan SM, Dimitrova D, Kanakry JA, Luznik L, Kanakry CG| | PubMed