University of California San Francisco

Biography

Arya Zarinsefat, M.D. is an Abdominal Transplant Fellow in the UCSF Department of Surgery. He completed his General Surgery residency training at UCSF in 2022. During his research years, he worked in Sarwal Lab at UCSF and completed the Advanced Training in Clinical Research certificate program through the UCSF Department of Epidemiology and Biostatistics.

Dr. Zarinsefat obtained a Bachelor of Arts in Chemistry from Johns Hopkins University completed his medical education at the University of Michigan, where he demonstrated early commitment to research by utilizing analytic morphometrics to predict perioperative outcomes. He excelled academically and clinically, and was selected to the Alpha Omega Alpha honor society. He continued to excel at UCSF during his general surgery residency. Dr. Zarinsefat was co-mentored by Dr. Minnie Sarwal (expertise with next-generation sequencing and bioinformatics) and Dr. Peter Stock (transplant surgery in HIV positive recipients) during his research years. Dr. Stock has tapped him to establish a university-wide database of all HIV-infected transplant recipients, and to follow their long term outcomes. 

 

 

 

 

 

Awards & Honors

Award Conferred By Date
UCSF-Gladstone Center For AIDS Research (CFAR) Mentored Scientist Award UCSF 2019/2020
"Filling a Void of Research Training for Transplant Surgeons” (FAVOR) T32 Training Grant NIH 2018/2020

Education

Institution Degree Dept or School End Date
University of Michigan M.D. Doctor of Medicine 05/2015
Johns Hopkins University B.A. Chemistry 05/2010

Clinical Interests

General Surgery

Transplant Surgery

Zarinsefat A, Terjimanian MN, Tishberg LM, Stein IC, Mazurek AA, Wang SC, Sonnenday CJ, Englesbe MJ. Perioperative ChangesIn Trunk Musculature. Oral Presentation presented at: Academic Surgical Congress, 8th Annual Meeting; 2013; New Orleans, LA.

Zarinsefat A, Kim EK, Bonn J, DeRoo S, Lee C, Stein I, Campbell DA, Englesbe MJ. The Role of Bowel Preparation In Improving Surgical Outcomes in Elective Colectomy. Oral Presentation presented at: Academic Surgical Congress, 8th Annual Meeting; 2013; New Orleans, LA.

Zarinsefat A, Syed SM, Hirose R. Initial results from the pilot Transplant Quality Improvement Project (TransQIP). Poster presented at: ASTS Winter Symposium; January 2019; Miami, FL

Zarinsefat A, Braun HJ, Syed SM, Orandi BJ, Roll GR. Do high-risk categories convey the wrong message to waitlisted patients – is it time to reconsider the absolute risk of graft loss?Poster presented at: American Transplant Congress; June 2018; Seattle, WA

Research Interests

Organ Transplantation in HIV-infected recipients

Microbiome in Transplantatio

Publications

MOST RECENT PUBLICATIONS FROM A TOTAL OF 27
  1. An Enhanced Role of Innate Immunity in the Immune Response After Kidney Transplant in People Living With HIV: A Transcriptomic Analysis.
    Zarinsefat A, Dobi D, Kelly YM, Szabo G, Henrich T, Laszik ZG, Stock PG| | PubMed
  2. 313.4: The tissue common response module (tCRM) score predicts treatment response for acute cellular rejection following pancreas transplant.
    Audrey E Brown, Yvonne M Kelly, Arya Zarinsefat, Worner Giulia, Raphael PH Meier, Minnie M Sarwal, Andrew Posselt, Zoltan G Laszik, Tara Sigdel, Peter Stock| | UCSF Research Profile
  3. 234.10: Using a Unique Repository of Pancreas Transplant Biopsies To Validate the Tissue Common Response Module (tCRM) Score as a Tool to Assess the Severity of Pancreas Transplant Rejection.
    Yvonne Kelly, Arya Zarinsefat, Raphael Meier, Minnie Sarwal, Peter Stock, Zoltan Laszik, Tara Sigdel| | UCSF Research Profile
  4. 411.2: Rejection After Liver Transplantation: What Can We Learn From Transcriptomic Analysis?.
    Hillary Braun, Dominic Amara, Arya Zarinsefat, Gyula Szabo, Zoltan Laszik, Peter G Stock, Nancy L Ascher| | UCSF Research Profile
  5. Considerations For Use of Propensity Score Matching in Specific Patient Populations-Reply.
    Zarinsefat A, Shui A, Stock P| | PubMed
  6. Consent to organ offers from public health service "Increased Risk" donors decreases time to transplant and waitlist mortality.
    Kelly YM, Zarinsefat A, Tavakol M, Shui AM, Huang CY, Roberts JP| | PubMed
  7. Long-term Outcomes Following Kidney and Liver Transplant in Recipients With HIV.
    Zarinsefat A, Gulati A, Shui A, Braun H, Rogers R, Hirose R, Ascher N, Stock P| | PubMed
  8. Use of the Tissue Common Rejection Module Score in Kidney Transplant as an Objective Measure of Allograft Inflammation.
    Zarinsefat A, Guerra JMA, Sigdel T, Damm I, Sarwal R, Chan-On C, Szabo G, Aguilar-Frasco JL, Ixtlapale-Carmona X, Salinas-Ramos C, Ramirez-Martinez L, Ramirez C, Vilatoba M, Morales Buenrostro LE, Alberu JM, Sarwal MM| | PubMed
  9. Single-Cell RNA Sequencing of Tocilizumab-Treated Peripheral Blood Mononuclear Cells as an in vitro Model of Inflammation.
    Zarinsefat A, Hartoularos G, Rychkov D, Rashmi P, Chandran S, Vincenti F, Yee CJ, Sarwal MM| | PubMed
  10. Single-cell RNA sequencing of Tocilizumab-treated peripheral blood mononuclear cells as an in vitro model of inflammation.
    Zarinsefat A, Hartoularos G, Chandran S, Yee CJ, Vincenti F, Sarwal MM| | PubMed
  11. Successful Long-Term Outcomes in HIV-Infected Transplant Recipients: Overcoming Hepatitis C.
    Arya Zarinsefat, Arushi Gulati, Ryutaro Hirose, Nancy L. Ascher, Mehdi Tavakol, Rodney Rogers, Peter G. Stock| | UCSF Research Profile
  12. Everolimus, an mTORC1/2 inhibitor, in ART-suppressed individuals who received solid organ transplantation: A prospective study.
    Henrich TJ, Schreiner C, Cameron C, Hogan LE, Richardson B, Rutishauser RL, Deitchman AN, Chu S, Rogers R, Thanh C, Gibson EA, Zarinsefat A, Bakkour S, Aweeka F, Busch MP, Liegler T, Baker C, Milush J, Deeks SG, Stock PG| | PubMed
  13. A TRANSCRIPTOMIC ANALYSIS COMPARING REJECTION IN KIDNEY BIOPSIES FROM HIV-INFECTED AND NON-INFECTED TRANSPLANT RECIPIENTS.
    Arya Zarinsefat, Yvonne M. Kelly, Dejan Dobi, Peter G. Stock, Zoltan G. Laszik| | UCSF Research Profile
  14. CONSENT TO ORGAN OFFERS FROM PUBLIC HEALTH SERVICE “INCREASED RISK” DONORS DECREASES TIME TO TRANSPLANT AND WAITLIST MORTALITY.
    Yvonne Kelly, Arya Zarinsefat, Mehdi Tavakol, Amy M. Shui, Chiung-Yi Huang, John Roberts| | UCSF Research Profile
  15. NOVEL HUMAN KIDNEY CELL SUBSETS IDENTIFIED BY MUX-SEQ.
    Andrew W. Schroeder, Swastika Sur, Priyanka Rashmi, Izabella Damm, Arya Zarinsefat, Matthias Kretzler, Jeff Hodgin, Tara Sigdel, George Hartoularos, Jimmie Chen Ye, Minnie M. Sarwal| | UCSF Research Profile
  16. SINGLE-CELL RNA SEQUENCING TO ASSESS THE EFFECT OF IL-6 RECEPTOR BLOCKADE IN KIDNEY TRANSPLANTATION.
    Arya Zarinsefat, Priyanka Rashmi, Andrea Da Silva, Tara Sigdel, Sindhu Chandran, Quizi Tang, Chun Ye, Flavio Vincenti, Minnie Sarwal| | UCSF Research Profile
  17. THE TISSUE COMMON RESPONSE MODULE (TCRM) SCORE PROVIDES A QUANTITATIVE OBJECTIVE BIOPSY SCORE TO ASSESS THE SEVERITY OF PANCREAS TRANSPLANT REJECTION.
    Yvonne Kelly, Arya Zarinsefat, Tara Sigdel, Raphael Meier, Minnie Sarwal, Peter Stock, Zoltan Laszik| | UCSF Research Profile
  18. USE OF TCRM TO AID DIAGNOSIS OF ALLOGRAFT REJECTION IN KIDNEY TRANSPLANTATION.
    Arya Zarinsefat, Juliane Liberto, Izabella Damm, Jose Guerra, Josefina Alberu, Minnie Sarwal| | UCSF Research Profile
  19. Long-term follow-up of beta cell replacement therapy in 10 HIV-infected patients with renal failure secondary to type 1 diabetes mellitus.
    Roll GR, Posselt AM, Freise J, Baird J, Syed S, Mo Kang S, Hirose R, Szot GL, Zarinsefat A, Feng S, Worner G, Sarwal M, Stock PG| | PubMed
  20. Chapter 34 Islet vs pancreas transplantation in nonuremic patients with type 1 diabetes.
    Arya Zarinsefat, Peter G. Stock| | UCSF Research Profile
  21. Cell-Free DNA and CXCL10 Derived from Bronchoalveolar Lavage Predict Lung Transplant Survival.
    Yang JYC, Verleden SE, Zarinsefat A, Vanaudenaerde BM, Vos R, Verleden GM, Sarwal RD, Sigdel TK, Liberto JM, Damm I, Watson D, Sarwal MM| | PubMed
  22. Outcomes associated with ablation compared to combined ablation and transilluminated powered phlebectomy in the treatment of venous varicosities.
    Obi AT, Reames BN, Rook TJ, Mouch SO, Zarinsefat A, Stabler C, Rectenwald JE, Coleman DM, Wakefield TW, Michigan Vein Health Program| | PubMed
  23. Update in preoperative risk assessment in vascular surgery patients.
    Zarinsefat A, Henke P| | PubMed
  24. Perioperative changes in trunk musculature and postoperative outcomes.
    Zarinsefat A, Terjimanian MN, Sheetz KH, Stein IC, Mazurek AA, Waits SA, Sullivan JA, Wang SC, Englesbe MJ| | PubMed
  25. A statewide colectomy experience: the role of full bowel preparation in preventing surgical site infection.
    Kim EK, Sheetz KH, Bonn J, DeRoo S, Lee C, Stein I, Zarinsefat A, Cai S, Campbell DA, Englesbe MJ| | PubMed
  26. Perioperative Changes in Trunk Musculature as a Predictor of One Year Mortality.
    A. Zarinsefat, M.N. Terjimanian, L.M. Tishberg, I.C. Stein, A.A. Mazurek, S.C. Wang, C.J. Sonnenday, M.J. Englesbe| | UCSF Research Profile
  27. The Role of Mechanical Bowel Preparation With Non-Absorbable Oral Antibiotics in Improving Surgical Outcomes in Elective Colectomy Within a State-Wide Collaborative.
    E.K. Kim, J. Bonn, S. DeRoo, C. Lee, I. Stein, A. Zarinsefat, M. Englesbe, D. Campbell| | UCSF Research Profile