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Ryutaro Hirose, M.D.

Ryutaro Hirose, M.D.

Professor of Clinical Surgery 
Division of Transplant Surgery
Associate Program Director,
UCSF General Surgery Residency Program
Surgical Medical Director, SRTR

Contact Information

(415) 353-1888 Clinical, Liver
(415) 353-1551 Clinical, Kidney and Pancreas
(415) 353-8783 Academic
Ryutaro.Hirose@ucsfmedctr.org   
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Education

  • Columbia College, Columbia University, B.A., Mathematics, 1981-85
  • Columbia University College of Physicians And Surgeons, M.D., 1985-89

Residencies

  • University of California, San Francisco, Intern and Resident, Surgery, 1989-92
  • University of California, San Francisco, Resident, Surgery, 1995-96
  • University of California, San Francisco, Chief Resident, Surgery, 1996-97 

Fellowships

  • University of California, San Francisco, Fellow, Transplant Surgery, 1997-99

Postdoctoral Training

  • University of California, San Francisco, Postdoctoral Fellow, Molecular Medicine, 1992-95

Board Certifications

  • American Board of Surgery, 1998

Clinical Expertise

  • Bile Duct Cancer (Cholangiocarcinoma)
  • Bile Duct Injuries
  • Bile Duct Strictures
  • Complex Cancer Resections
  • Fulminant Hepatic Failure
  • Hepatitis B
  • Hepatitis C
  • Hepatocellular Carcinoma (Liver Cancer)
  • Kidney Transplantation
  • Liver Resection
  • Liver Transplantation
  • Living Donor Kidney Transplantation
  • Living Donor Liver Transplantation
  • Pancreas Transplants
  • Pediatric Kidney Transplantation
  • Pediatric Liver Transplantation
  • Portal Hypertension
  • Radio Frequency Ablation (RFA)
  • Surgical Shunts

Research Interests

  • Ischemia Reperfusion Injury in Fatty Livers
  • Ischemia-reperfusion Injury in Kidneys and Hyperglycemia
  • Living Donor Liver Transplantation
  • Non-melanoma Skin Cancer in Organ Transplant Patients
  • Outcomes in Renal Transplant Recipients
  • Pathogenesis of Focal Segmental Glomerulosclerosis

Website Links

Biography

Ryutaro Hirose is a Professor of Clinical Surgery at UCSF and performs liver, kidney and pancreas transplants. After graduating from Columbia College of Physicians and Surgeons, he completed his clinical and research training at UCSF as a resident in general surgery as well as a fellow in molecular medicine and transplantation surgery. His research interests include renal and hepatic ischemia - reperfusion injury, immune monitoring and skin cancer in transplant recipients. He has received funding from the NIH, NKF, UCSF, ASTS, and private industry. He is also actively involved with teaching students and residents. Dr. Hirose is currently the Associate Program Director for the General Surgery Residency at UCSF. In 2019, Dr. Hirose was appointed Surgical Medical Director of the  Scientific Registry of Transplant Recipients (SRTR).

Research Overview

Dr. Hirose's research focus is ischemia-reperfusion injury and potential interventions to ameliorate renal and hepatic I-R injury. His group uses animal models, performs clinical and translational research as well as research on deceased donors. He collaborates with Dr. Claus Niemann, MD from the Dept. Anesthesia and they are co-Directors of the Ischemic Organ Injury Lab.

Research Pathways

Clinical Trials

Data provided by UCSF Profiles, powered by CTSI

Publications

MOST RECENT PUBLICATIONS FROM A TOTAL OF 87
Data provided by UCSF Profiles, powered by CTSI
  1. Boyarsky BJ, Werbel WA, Durand CM, Avery RK, Jackson KR, Kernodle AB, Snyder J, Hirose R, Massie IM, Garonzik-Wang JM, Segev DL, Massie AB. Early National and Center-level Changes to Kidney Transplantation in the United States During COVID-19 Epidemic. Am J Transplant. 2020 Jun 28. View in PubMed
  2. Braun HJ, Dodge JL, Grab JD, Schwab ME, Liu IH, Glencer AC, Stock PG, Hirose R, Roberts JP, Ascher NL. Live Donor Liver Transplantation in the United States: Impact of Share 35 on Live Donor Utilization. Transplantation. 2020 May 18. View in PubMed
  3. Jain M, Duh QY, Hirose R, Sosa JA, Suh I. A model for the institutional adoption of innovative surgical techniques. Surgery. 2020 May 03. View in PubMed
  4. Snyder JJ, Musgrove D, Zaun D, Wey A, Salkowski N, Rosendale J, Israni AK, Hirose R, Kasiske BL. The Centers for Medicare and Medicaid Services' proposed metrics for recertification of organ procurement organizations: Evaluation by the Scientific Registry of Transplant Recipients. Am J Transplant. 2020 Mar 11. View in PubMed
  5. Vagefi PA, Bertsimas D, Hirose R, Trichakis N. The rise and fall of the model for end-stage liver disease score and the need for an optimized machine learning approach for liver allocation. Curr Opin Organ Transplant. 2020 Apr; 25(2):122-125. View in PubMed
  6. View All Publications

Videos

Data provided by UCSF Profiles, powered by CTSI
  1. Live Donor Liver Transplants and Surgery for Non-HCC
  2. UCSF Kidney Transplant Update: State of Transplantation, New Drugs, New Trials, Transplant Controversies
  3. 2010 Kidney Transplant: Update New Methods to Detect Anti-HLA Antibodies, Current Protocols for Patients with Donor Specific Antibodies
  4. UCSF Kidney Transplant Update 2011: Biomarkers to Monitor Immunosuppression
  5. Kidney Transplants: Who Needs One? How Do We Do It?

In the News

  • UCSF Transplant Surgeon Ryutaro Hirose, M.D. Instrumental in New Liver Transplant Donation Guidelines

    UCSF News Services - Scott Maier - February 06, 2020
    The Organ Procurement Transplantation Network (OPTN) recently updated the liver distribution policy to provide better efficiency and fairness for transplant patients – regardless where they live, what hospital they choose for care or how sick they must be before being likely to get a transplant – and a UC San Francisco transplant surgeon was instrumental in its development. UCSF Health transplant surgeon Ryutaro Hirose, M.D. was former chair of the OPTN Liver and Intestinal Organ [...]

  • Dr. Ryutaro Hirose Appointed Surgical Medical Director of the Scientific Registry of Transplant Recipients (SRTR)

    SRTR News - SRTR Staff - November 20, 2019
    UCSF transplant surgeon Ryutaro Hirose, M.D. has been appointed Surgical Medical Director of the  Scientific Registry of Transplant Recipients (SRTR). Below is the official announcement: The Scientific Registry of Transplant Recipients (SRTR) is pleased to announce the addition of Dr. Ryutaro (Ryo) Hirose as Surgical Director of the SRTR. Dr. Hirose serves as Professor of Clinical Surgery at the University of California, San Francisco (UCSF) and will continue in that role while lending his [...]

  • UCSF General Surgery Residency Program Ranked No. 1 in Western U.S. in Annual Doximity Survey

    Department of Surgery - Richard Barg - August 23, 2018
    The UCSF General Surgery Residency was ranked No. 1 in research output and by reputation among sister programs in California and across the western U.S. in the Doximity 2018-19 annual survey. Nationally, the program placed in the 99th percentile for research output.  The residency program is led by Department Chair Julie Ann Sosa, M.D., M.A., FACS, Program Director Linda M. Reilly, M.D., Associate Directors Ryutaro Hirose, M.D., Kenzo Hirose, M.D., and Lygia Stewart, M.D., and Administrative [...]

  • UCSF Department of Surgery Faculty Honored with Excellence in Teaching Awards

    UCSF Department of Surgery - Richard Barg - October 02, 2017
    The Haile T. Debas Academy of Medical Educators presented seven Department of Surgery faculty with the Excellence in Teaching Award for 2017 at a ceremony on September 11th at the UCSF School of Nursing, held in conjunction with the Academy's induction of new members. The Academy's Excellence in Teaching Awards are peer-nominated, and honor outstanding front-line teachers of medical students, residents, and fellows who often go unrecognized. These teachers create and encourage an intellectually [...]

  • UCSF Clarifies Policy on Marijuana Use and Transplant Eligibility

    UCSF Transplant Surgery - Richard Barg - June 01, 2017
    ABC News San Francisco (KGO) reports on the case of a Utah man, recovering from a lung transplant in Pennsylvania after a Utah hospital refused to put him on their transplant list because of past marijuana use. (The man subsequently died after the airing of the KGO story.) UCSF transplant surgeon, Ryutaro Hirose, M.D., was interviewed by KGO and regarding the policy on this is issue at UCSF. "We've recently liberalized our criteria regarding marijuana," said Dr. Ryutaro Hirose who is a [...]

  • UCSF Research Team Shows that Mild Hypothermia in Deceased Organ Donors Improves Function in Kidney Transplant Recipients

    UCSF Transplant Surgery - Richard Barg - July 30, 2015
    UCSF News reports on a just published study in the The New England Journal of Medicine in which mild hypothermia in deceased organ donors was found to significantly reduce delayed graft function in kidney transplant recipients compared with normal body temperature. The lead author of the study is Claus Niemann, MD, Professor of Anesthesia and Surgery at UCSF, and co-Director of the Ischemic Organ Injury Lab. The findings in the study could lead to an increase in the availability of kidneys for [...]

  • Teen Liver Transplant Recipient to Honor Donor at 2013 Rose Parade

    UCSF Transplant Surgery - December 28, 2012
    The Garcia family and their transplant team
    Alfonso Garcia and his parents pose with the UCSF medical team that cared for him during his 2010 life-saving liver transplant. From left: mother Marta Garcia; Emily Perito, MD; nurse practitioner Susan Diaz, MSN; Garcia; Philip Rosenthal, MD; and father Oscar Garcia. Alfonso Garcia still carries around a baseball cap that belonged to a 22-year-old man who passed away in 2010 having never met him. But the cap is just a small token of an even bigger reminder that the 18-year-old college [...]

  • UCSF Patients Part of Nation's Longest Living Kidney Transplant Chain

    UCSF Transplant Surgery - March 15, 2012
    "Neither man had a donor who was a match. But each had a family member willing to donate a kidney to a stranger, allowing them all to be part of chain which would, in turn, give Baty and Cienfuegos kidneys from other strangers. With 17 participating hospitals in 11 states, the chain consisted of 30 people willing to give up their kidney, matched with 30 more who needed one to survive. UCSF surgeons Andrew Posselt, M.D., Ph.D. and Ryutaro Hirose, M.D., performed the transplants on Baty and [...]

  • UCSF Receives Grant to Improve Outcomes in Organ Donor Transplantation

    UCSF Transplant Surgery - October 20, 2011
    UCSF News reports on the award of a $2 million grant by the Health Resources and Services Administration (HRSA) to a team led by Claus Niemann, MD, Associate Professor in the UCSF Department of Anesthesia and Perioperative Care and co-Director of the Ischemic Organ Injury Lab to improve outcomes in organ donor transplantation.  The grant was awarded to Niemann and his collaborators including John Feiner, MD, as well as Ryutaro Hirose, MD, and John Roberts, MD, chief of the UCSF Transplant [...]

  • UCSF Liver Transplant Team Shares Expertise in Latin America

    UCSF Transplant Surgery - March 23, 2011
    Niemann
    "Previously, Uruguay had tried to go it alone, but high mortality rates soon caused doctors to shut the program down. After their initial visit, the UCSF transplant team, including anesthesiologist Claus U. Niemann, MD (pictured first), and surgeons Ryutaro Hirose, MD (pictured second), and Peter Stock, MD, PhD, (pictured third) continued to consult with the team in Uruguay, guiding them through everything from patient selection procedures to the use of immunosuppressive medications [...]

  • The Domino Effect - Woman gets new liver, gives her old one to save another life

    UCSF Transplant Surgery - August 22, 2000
    "The next day, surgeons at the University of California at San Francisco performed a rare liver transplant called a ``domino transplant,'' the first in the Bay Area and one of just a handful done in the United States. ........................Her choice was to have a liver that will give her a disease in 30 years, or die of cancer in the next year,'' said Dr. Ryutaro Hirose (pictured left), the surgeon for both transplants. ``She jumped at the chance, and most people would.''

Patient Stories

  • Alfonso Garcia

    A Young Man Saves Teen's Life

    UCSF Benioff Children's Hospital -  by Kendra Mayfield - August 01, 2011
    Alfonso Garcia was just like any other typical healthy and active 16-year-old. He dreamed of attending the U.S. Military Academy at West Point, boxing, and serving in the military like his two other brothers. Then, in January 2010, he suddenly started feeling sick. He became feverish, anemic, fatigued and jaundiced. Alfonso found out that he had Wilson's disease, a rare genetic disorder in which copper in the body isn't properly eliminated and instead accumulates, damaging the liver and nervous system. Alfonso and his family received a grave[...]
    Story Categories: Liver TransplantWilson Disease

 

 
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